At PEAKANDPICK, we’re always looking for wellness brands that go beyond trends and lead with science. Pendulum Therapeutics does exactly that. Founded by researchers from Johns Hopkins, Stanford, and Harvard, Pendulum develops precision probiotics based on deep microbiome research and real-world clinical data to help transform your gut microbiome.
Their mission is simple: unlock the power of the gut microbiome to support better health. Using proprietary DNA sequencing and in-house strain development, Pendulum offers targeted probiotic formulas that support digestion, metabolic wellness, and gut balance—without relying on generic “one-size-fits-all” blends.
Let’s take a closer look at three of their most innovative products—Akkermansia, Metabolic Daily, and Glucose Control—and why this brand is unlike anything else in the probiotic space.
What Makes Pendulum Different
Pendulum stands out because they don’t outsource strain development or manufacturing. Every product is developed in-house—from sequencing to capsule—using Pendulum’s proprietary strain bank. They’re also the first and only brand to offer Akkermansia muciniphila in a shelf-stable form, a next-gen strain being studied by leading researchers for its role in gut barrier support and microbiome balance.
What you won’t find in their products: fillers, unnecessary additives, or borrowed strains. All formulas are non-GMO, vegan, gluten-free, and third-party tested.
| Feature | Pendulum Therapeutics |
|---|---|
| Developed by microbiome scientists | ✅ (Harvard, Stanford, Johns Hopkins) |
| In-house DNA sequencing & strains | ✅ |
| Proprietary & clinically studied | ✅ |
| Clean label, non-GMO, USA-made | ✅ |
| HSA/FSA eligible | ✅ |
Pendulum Akkermansia
Pendulum’s Akkermansia is a single-strain probiotic featuring Akkermansia muciniphila—a key strain in the gut often linked to microbial diversity and gut lining support. This strain wasn’t available in supplement form until Pendulum introduced it using patented technology.
Each capsule includes Akkermansia muciniphila and chicory inulin, a prebiotic that helps nourish beneficial bacteria. It’s designed to be taken once daily with food.
Pendulum also outlines what to expect as the supplement becomes part of your daily routine:
| Timeline | What to Expect |
|---|---|
| Week 1–3 | You may experience mild digestive changes—your microbiome is adjusting. |
| Month 1–2 | Early signs of balance may appear, though results vary by individual. |
| Month 3+ | The full benefit may emerge as the microbiome stabilizes and adapts. |
| Plan | Price | Savings | Delivery |
|---|---|---|---|
| Membership (3-month) | $168 | 41% off | Ships every 90 days (90 ct) |
| Membership (1-month) | $59 | 37% off | Ships monthly (30 ct) |
| One-time Purchase | $95 | — | 30-count bottle |
Free shipping on memberships
HSA/FSA eligible
No refrigeration required
Based on preclinical studies. Not intended to diagnose or treat any disease.
Pendulum Metabolic Daily
Metabolic Daily is a 4-in-1 formula designed to support digestion, energy metabolism, immune health, and gut microbial balance. It contains five targeted strains—several of which are proprietary to Pendulum—and is paired with chicory inulin to help nourish the good bacteria.
This product is ideal for everyday use and fits seamlessly into a broader wellness routine. The capsule is delayed-release for targeted gut delivery and taken once daily with food.
| What It Supports |
|---|
| Daily digestive balance and fiber breakdown* |
| Support for metabolic energy utilization* |
| General immune support linked to gut balance* |
| Plan | Price | Savings | Delivery |
|---|---|---|---|
| Membership (3-month) | $139 | 41% off | Ships every 90 days |
| Membership (1-month) | $49 | 38% off | Ships monthly |
| One-time Purchase | $79 | — | 30-count bottle |
Free shipping on memberships
HSA/FSA eligible
Non-GMO, vegan, gluten-free
*Based on preclinical studies
Pendulum Glucose Control
Glucose Control is Pendulum’s most research-backed supplement. It contains the same 5-strain probiotic blend as Metabolic Daily but in higher doses, designed for individuals focused on post-meal nutritional balance. It includes chicory inulin and is taken twice daily—morning and evening with food.
According to Pendulum’s internal clinical study (Perraudeau et al., 2020), participants using Glucose Control saw the following results:
- 32.5% reduction in post-meal glucose spikes*
- 0.6-point reduction in A1C*
While these outcomes are based on controlled settings, Pendulum clearly communicates the intended use of this product as a nutritional supplement—not a medical intervention.
| Plan | Price | Savings | Delivery |
|---|---|---|---|
| Membership (3-month) | $282 | 41% off | Ships every 90 days (3 x 60 ct) |
| Membership (1-month) | $99 | 37% off | Ships monthly (60 ct) |
| One-time Purchase | $159 | — | 60-count bottle |
Free shipping on memberships
HSA/FSA eligible
Two capsules per day with meals
*As always, consult your healthcare provider before beginning a new supplement.
Final Thoughts
Pendulum is at the forefront of gut science, bringing together research, precision, and product transparency in a way few supplement brands do. With targeted strains like Akkermansia muciniphila, formulations designed to support specific health goals, and clean ingredient labels, their approach feels thoughtful, credible, and refreshingly direct.
Whether you’re looking to support gut balance, better metabolize nutrients, or take a nutritional approach to post-meal glucose support, Pendulum offers a lineup that’s as smart as it is simple.
👉 Explore Pendulum’s full collection here
If you’re exploring ways to support your body naturally, you may also enjoy our feature on Alkaline Herb Shop’s Immunity Boosting Bundle. Like Pendulum, it focuses on plant-based, high-integrity ingredients that support everyday wellness. Read the blog here to discover how herbal blends can complement your probiotic routine.
This blog is for informational purposes only. These statements have not been evaluated by the FDA. Pendulum products are not intended to diagnose, treat, cure, or prevent any disease.
